Differential recognition of Plasmodium falciparum merozoite surface protein 2 variants by antibodies from malaria patients in Brazil.

نویسندگان

  • Kelly A Kanunfre
  • Fabiana M S Leoratti
  • Erika H E Hoffmann
  • Rui R Durlacher
  • Antônio W Ferreira
  • Sandra L Moraes-Avila
  • Marcelo U Ferreira
چکیده

Four variants of merozoite surface protein 2 (MSP-2) of Plasmodium falciparum were used in serology to examine whether changes in repeat units affect its recognition by antibodies during infection with parasites of known MSP-2 types. The results indicate that variation in MSP-2 repeats may represent a mechanism for parasite immune evasion.

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عنوان ژورنال:
  • Clinical and diagnostic laboratory immunology

دوره 10 5  شماره 

صفحات  -

تاریخ انتشار 2003